Course Description. Introduction to and critical assessment of the concepts, technologies and practical challenges of developing a new medicine and bringing it to market. Pharmacology fundamentals, preclinical drug discovery, clinical trials, manufacturing and regulatory issues, as well as financing and marketing are discussed for small molecule, biologic and cellular therapies. Faculty from MIT, Harvard and industry present introductory and topic-specific lectures (case studies) and students engage in weekly news updates and collaborative research projects. The course uses a medical, economic and societal issues associated with drug development now and in the future.